为促进寄生虫学的转化应用方面的研究与发展，探索/验证基于寄生虫病诊断及预后技术，以及虫源性分子及其诱导特异性应答的转化应用价值，并分享寄生虫来源分子诊断和治疗的新思路，Zoonoses 拟在全球范围内就“Parasitic infections for translational medicine: the new story（寄生虫感染与转化医学—新故事）”这一主题面向广大学者征集相关稿件。

投稿截止日期：2022年9月30日

征稿主题

Parasitic infections for translational medicine: the new story!

寄生虫感染与转化医学—新故事

引言：

寄生虫病对热带和亚热带地区亿万人民和全世界的家禽家畜危害很严重，造成的健康、生命和经济损失难以估量。然而除了致病性以外，越来越多的学者还关注在基于这些寄生虫感染的潜在临床应用价值。其灵感主要来源于“卫生假说”，该假说认为在生命早期某些病原体暴露减少会导致某些免疫相关疾病的高发。大量的流行病学资料支持这一观点，即一些人畜共患寄生虫感染（例如血吸虫、钩虫）与炎症肠道疾病、过敏性疾病、肥胖症的患病率降低密切相关，其潜在的原因可能与寄生虫感染后诱导产生的2型免疫和/或调节性T细胞应答等有关。更好地挖掘这些现象背后的生物学机制对于探索寄生虫介导的转化应用价值意义重大。

寄生虫与宿主是一个特殊的协同进化系统，它在长期漫长的演化过程中与宿主形成了相互适应性。在此过程中，寄生虫分泌/排泄的众多成分发挥极其重要的作用。这些分子通过影响宿主先天免疫以及后续的适应性免疫，建立了持久的、高度特异性的免疫应答水平。这些特异性的应答能力对众多感染性、非感染性疾病的诊断和治疗具有潜在的临床价值。因此，寻找寄生虫的新基因、新分子和新靶点对于基于寄生虫的转化应用价值至关重要，探索此类分子和靶点的免疫及非免疫学机制尤为迫切。

本期特刊旨在介绍和讨论涉及寄生虫衍生分子对于疾病的诊断及创新疗法的发展，为寄生虫及其他疾病的诊治提供新的思路和科学的理论依据。

征稿信息：

本专刊欢迎原创研究、综述、小综述、假设和理论研究等前瞻性文章，方向包括但不限于以下内容：

1. 人畜共患寄生虫病的流行病学、防治体系和疫苗研制

2. 病原体衍生分子在免疫应答中的新发现

3. 寄生虫病的潜在诊断和预后标志物

4. 基于寄生虫分子（包括蛋白质、miRNA和细胞外囊泡（EVs）等）的各种疾病治疗研究。

5. 宿主-寄生虫相互作用

此专刊在征稿中，截稿时间：

Manuscript - 2022 年 9 月 30 日

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期刊官网

https://zoonoses-journal.org/index.php/2021/09/22/call-for-papers-theme-issue-parasitic-infections-for-translational-medicine/

徐志鹏副教授联合澳大利亚和马来西亚学者开启“寄生虫感染的转化医学”专题组稿，欢迎各位关注、转发、投稿！

客座主编

徐志鹏

医学博士， 副教授

澳大利亚昆士兰医学研究院（QIMR Berghofer Medical Research Institute）访问学者（2019.3~2020.3），江苏省高校“青蓝工程”优秀青年骨干教师，南京医科大学“优秀中青年教师支持计划”优秀青年骨干教师培养对象。长期关注寄生虫感染后导致的宿主脑与肝脏免疫病理形成的分子学机制的研究，尤其是关注虫源性分子对机体免疫细胞的作用机制。目前以第一作者/通讯作者身份在“Nature Neuroscience”、“Nature Communications”、“Theranostics”、“Obesity”等国际高水平杂志上发表多篇学术论文，第一/通讯作者论著累计影响因子>80分。以第一/四/四申请人的身份申请国家发明专利三项。以项目主持人身份获得国自然基金青年基金、江苏省自然科学基金青年基金、江苏省高等学校自然科学研究面上项目，南京医科大学生殖医学国家重点实验自主课题等项目。担任第一届江苏省预防医学会全球卫生专业委员会委员，担任《中国寄生虫学与寄生虫病杂志》青年编委，同时受邀担任Journal of Immunology Research、BMC immunology国际期刊杂志的Academic editor。承担人体寄生虫学、病原生物学、人类疾病病原病理学基础、Medical Parasitology、医学英文文献导读等本科、硕士研究生课程。指导本科生开展各类科研实践活动。

HONG YOU

澳大利亚QIMR Berghofer医学研究所，

分子寄生虫学实验室，博士

Hong You is currently working as the senior research officer in Molecular Parasitology Laboratory in QIMR Berghofer Medical Institute and the Senior Lecturer in School of Veterinary Science in University of Queensland. Dr. You focus on the study of gene editing of schistosoma and the parasites-derived molecules on the regulation of host immunity. She has published more than 60 papers. Dr. You has lead projects as Chief Investigator including QIMR Berghofer Medical Research Institute seed grant, Australian Infectious Diseases Research Centre (AID) seed grant, Australian National Health and Medical Research Council (NHMRC) project grant, NHMRC Early Career Fellowship, Australian Infectious Diseases Research Centre (AID) seed grant, and Josephine Mackerras Training Fellowship Supported by Australian Centre for Vaccine Development for visiting Emory University in Atlanta and learning new vaccine technologies and attending American Society of Tropical Medicine and Hygiene 61st Annual Meeting in Atlanta, etc. Dr. You has been Awards for the Australian Society for Parasitology Network for Parasitology Researcher Exchange Travel Award for visiting Baylor University, Travel Award for visiting Yangzhou University and Jiangsu Institute of Parasitic Diseases, Australian Society for Parasitology Network for Parasitology Researcher Exchange Travel Award for visiting George Washington University, Invitation to attend the Australian Museum Eureka prizes award Ceremony in Sydney supported by Australian Infectious Diseases Research Centre, etc. She severs as the reviewer and invited as guest editor for several journals, including Nature Communication, Pathogens, FASEB, BioEssays, Frontiers Cellular and Infection Microbiology, Frontiers in Genetics, etc.

Leow Chiuan Yee

马来西亚理科大学药学院，博士

Leow Chiuan Yee is currently working as Senior Lecturer, Principal Investigator, as well as the Course Coordinator in Universiti Sains Malaysia, Malaysia. He had visited QIMR Berghofer Medical Institute in Australia and used to identify the second receptor for PD-L2 and undertook the original research to show that targeting this molecule was protective against malaria. To date, he has attained 14 years of academic, research and industrial-consultancy experiences. Dr. Yee was awarded for Top Performing Paper (highest read and cited in 2018) 2019—Pathogen and Global Health (Editorial by Imperial College London); Australian Research Fellowship 2019—Griffith University, Australia; USM Sanggar Sanjung Award (Excellence in Publication) 2016—Universiti Sains Malaysia, Malaysia, etc., and severed as Australian Society for Parasitology, Malaysian Society of Parasitology and Tropical Medicines, Young Scientists Network – Academy of Sciences Malaysia, and International Society for Infectious Diseases. Dr. Yee has been served as Seasonal Tutor (University of Queensland, Australia), Senior Lecturer and Postgraduate (Masters) Course Coordinator at Universiti Sains Malaysia (Malaysia), Lecturer and Course Coordinator at Faculty of Pharmacy, Universiti Teknologi MARA (Malaysia), and Lecturer, Scientific Officer and Laboratory Safety Coordinator at AIMST Universiti (Malaysia). He has supervised more than 20 research projects and 9 postgraduate research students. Dr. Yee has Published more than 20 SCOPUS/ISI indexed research papers in the field of cell biology, biochemistry, pharmacology, immunology, vaccinology, bioinformatics, microbiology and biomedical science. Also, he severs as the reviewer of MSc (Molecular Medicine) program, accredited by Malaysia Qualification Agency (MQA).