《光动力生物学》特刊欢迎投稿

Photodynamic Biology

Edited by Zong Jie Cui 

MDPI Journals:

Biomedicines 

Cells

Keywords: Photodynamic action; singlet oxygen; cellular functions; functional proteins; autophagy; photosensitizer; phototoxicity; bioluminescent proteins as light sources

Websites:

https://www.mdpi.com/journal/biomedicines/special_issues/92AGFK0R34

https://www.mdpi.com/journal/cells/special_issues/S1335EUW11

Photodynamic action as defined originally is oxygen-dependent. The extensively studied type II photodynamic action involving the excited state molecular oxygen, the delta singlet oxygen (Δ¹O₂), modulates numerous cellular functions, including cell secretion, muscle contraction, cellular signaling, cell death and senescence, autophagy, gene transcription and translation, development, and protein oxidation. Although photodynamic action has been studied extensively both aiming for diagnosis, therapy, and as a research tool to tease apart specific cellular and molecular details, studies aiming to define mechanisms of action at the cellular and molecular levels are scattered in the literature, in large numbers of journals in multiple disciplines. This special issue aims to call for a series of clearly defined cases of photodynamic modulation of biological activities, for example modulation of all categories of functional proteins as defined by the International Union of Basic and Clinical Pharmacology (https://bpspubs.onlinelibrary.wiley.com/toc/14765381/2021/178/S1): 

1/ G protein coupled receptors; 

2/ ionic channels; 

3/ transporters; 

4/ enzymes; 

5/ catalytic receptors; 

6/ nuclear hormone receptors; 

7/ other functional proteins.

The biological or enzyme-catalyzed generation, reaction, and quenching of delta singlet oxygen of physiological and biochemical significance will also be of particular interest to this special issue. The focus of the contribution could also be the light source (bioluminescence, for example) to drive the photodynamic action, or the photosensitizer (the genetically encoded protein photosensitizers, for example) and their tagging patterns to the target of interest (TOI).

It is the hope of this special issue sponsored by multiple journals at MDPI that by calling for this special issue, the field will be advanced in a significant way, and a few important topics will be identified for future investigations in the next decade or beyond.

Contributions could be original papers, comments, opinions, or mini-reviews focused on a pivotal topic in the photodynamic biology field.