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上传于 2017-1-4 16:31 (23 KB)

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IP: 124.115.70.*   JANEWANGJK55 发表了评论   2017-1-4 16:31
So far, 16 blaNDM gene variants have been discovered and assigned in the Lahey Clinic database, and some variants are found to confer elevated carbapenem resistance.     Accordingly, NDM producers are now on the top list of carbapenemase producers in European countries such as the UK and even in France.
IP: 124.115.70.*   JANEWANGJK55 发表了评论   2017-1-4 16:55
Plasmid-mediated imipenem-hydrolyzing enzyme KPC-2
IP: 124.115.70.*   JANEWANGJK55 发表了评论   2017-1-4 16:58
belonging to several incompatibility groups, ***.
IP: 124.115.70.*   JANEWANGJK55 发表了评论   2017-1-4 16:59
these genes are located mostly onto conjugative plasmids.
IP: 124.115.67.*   JANEWANGJK55 发表了评论   2017-1-5 10:16
ranging from pneumonia to diarrhea to bacteraemia. However, the recent appearance of β-lactamases capable of hydrolyzing carbapenems, in addition to other mechanisms of carbapenem resistance,
IP: 124.115.69.*   JANEWANGJK55 发表了评论   2017-1-11 10:04
complement(34347..35360)
                     /gene="intI1"
                     /function="involved in the insertion of antibiotic
                     resistance genes into plasmids and transposons, belongs to
                     the 'phage' integrase family"
                     /inference="protein motif:HMMPfam:PF00589"
                     /inference="protein motif:HMMPfam:PF02899"
                     /inference="protein motif:UniProt:INT2_SALTI"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase"
                     /protein_id="CCN79882.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATP
                     HTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLT
                     SER"

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